Index of 2003 Publications
- Gazit A, Yee K,
Uecker A, Bohmer FD, Sjoblom T, Ostman A, Waltenberger J, Golomb G, Banai S, Heinrich MC, Levitzki A.
Tricyclic quinoxalines as potent kinase inhibitors of PDGFR kinase, Flt3 and Kit..
Bioorg Med Chem. 2003 May;11(9):2007-18.
PMID: 12670652
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O'Farrell,A.M.; Abrams,T.J.; Yuen,H.A.;
Ngai,T.J.; Louie,S.G.; Yee,K.W.H; Wong,W.M.; Lee,L.B.;
Town,A.; Smolich,B.D.; Manning,W.C.; Murray,L.J.;
Heinrich,M.C.; Cherrington,J.M. SU11248
is a novel FLT3 tyrosine kinase inhibitor with
potent activity in vitro and in vivo.Blood 2003.
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Pub Med ID#12531805
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Heinrich,M.C.; Corless,C.L.;
Duensing,A.; McGreevey,L.; Chen,C.J.; Joseph,N.;
Singer,S.; Griffith,D.J.; Haley,A.; Town,A.; Demetri,G.D.;
Fletcher,C.D.M.; Fletcher,J.A. PDGFRA activating
mutations in Gastrointestinal Stromal Tumors.
Science, Vol 299, Issue 01/31/2003, Page 708
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PMID: 1252257
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Bauer S, Corless CL, Heinrich MC, Dirsch O, Antoch G, Kanja J, Seeber S, Schütte J.
Response to imatinib mesylate of a gastrointestinal stromal tumor with
very low expression of KIT. Cancer Chemother Pharmacol. 2003 Mar;51(3):261-5
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PMID: 12655446
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Madani A, Kemmer K, Sweeney C, Corless C, Ulbright T, Heinrich M, Einhorn L.
Expression of KIT and epidermal growth factor receptor in chemotherapy refractory non-seminomatous germ
cell tumors. Ann Oncol. 2003 Jun;14(6):873-80.
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PMID: 12796025
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Heinrich M, Corless C, Demetri G, Blanke C, von Mehren M, Joensuu H, McGreevey L, Chen C, Kiese B,
Eisenberg B, Roberts P, Singer S, Fletcher C, Silberman S, Dimitrijevic S, Fletcher J.
Kinase mutations and imatinib mesylate response in patients with metastatic gastrointestinal stromal tumor.
J Clin Onc 21:4342-4349, 2003.
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PMID: 14645423
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Cruz F III, Rubin B, Wilson D, Town A, Schroeder A, Haley A, Bainbridge T, Heinrich M, Corless C.
Absence of BRAF and NRAS mutations in uveal melanoma. Cancer Res. 2003 Sep 15;63(18):5761-6
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PMID: 14522897
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O'Farrell AM, Foran J, Fiedler W, Serve H, Paquette R, Cooper M, Yuen H, Louie S, Kim H, Nicholas S,
Heinrich M, Berdel W, Bello C, Jacobs M, Scigalla P, Manning W, Kelsey S, Cherrington J.
An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid
leukemia patients.Clin Cancer Res. 2003 Nov 15;9(15):5465-76.
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PMID: 14654525