
Recent Publications:
A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number. Lab Invest. 2010 Jun 14. [Epub ahead of print] (Click here to view)
Primary Extragastrointestinal Stromal Tumor of the pleura: Report of a unique case with genetic confirmation. Am J Surg Pathol. 2010 Jun;34(6):907-12. (Click here to view)
A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells. Leukemia. 2010 Jan;24(1):44-50. (Click here to view)
Comparison of Two Doses of Imatinib for the Treatment of Unresectable or Metastatic Gastrointestinal Stromal Tumors: A Meta-Analysis of 1,640 Patients. J Clin Oncol. 2010 Mar 1;28(7):1247-53. Epub 2010 Feb 1. (Click here to view)
Prevalence and prognostic significance of KIT mutations in pediatric core binding factor AML patients enrolled on serial pediatric cooperative trials for de novo AML. Blood. 2010 Jan 7. [Epub ahead of print] (Click here to view)
News and Updates:
May 2010
On May 19th, the GIST Cancer Research Fund generously donated $165,000 to the Heinrich-Corless Research Lab at the GCRF Grant Presentation Breakfast at OHSU. Without this support, we would not be able to continue to help find a cure for this terrible disease. On a special note, this year, the GCRF was able to reach their $1 million goal, an impressive milestone in their continued efforts to eradicate this devastating cancer. This year's GCRF group is shown in the photo below, during their tour of OHSU.

October 2009
In the early October of 2009, Dr. Carol Beadling represented the Heinrich-Corless laboratory group at the GIST Cancer Research Fund Walk for a Cure held in New York. Later that month, Dr. Michael Heinrich participated in the San Jose Walk for a Cure. Dr. Heinrich is shown in the photo below, along with the San Jose Walk for a Cure Co-Organizer, Irene Wing (center), and the Chairperson of the GIST Cancer Research Fund, Tania Stutman (right).
April 2009
On April 28th, Dr. Heinrich spoke to the Life Raft Group about "Optimizing Gleevec Therapy with Plasma Testing."
This presentation included the role of plasma testing, its logistics, who might benefit from this testing,
and how to interpret the results. Visit the link above to view the presentation.
On April 15th, the Gist Cancer Research Fund presented a generous donation in the amount of $150,000 to the Heinrich-Corless Research Lab at the GCRF Grant Presentation Breakfast at OHSU. This incredible gift is greatly appreciated, especially during these difficult economic times. Without this support, we would not be able to continue to help find a cure for this terrible disease.

Dr. Heinrich and Dr. Corless accepting the generous gift from The GIST Cancer Research Fund.
October 2008
On October 26th, 2008, Dr. Mike Heinrich traveled to Santa Clara, California, to participate in the West Coast GIST Cancer Research Fund Walk for a Cure. Dr. Heinrich is shown here with GIST patients and fellow GIST researcher Dr. Matt Van de Rijn of Stanford University School of Medicine.
(L-R) Barbara Livermore, Dr. Mike Heinrich, Jen Bayles, Dr. Matt Van de Rijn, and Vadim Schukin.
July 2008
The Life Raft Group has renewed research support grants to Drs. Michael Heinrich and Christopher Corless. The new grants, totaling $360,000 over two years, will be used to explore the activity of next-generation tyrosine kinase inhibitors (TKIs), study mechanisms of TKI resistance, and search for alternative oncogenic mechanisms in so-called wild-type GISTs. The work will be conducted collaboratively with other members of the Life Raft GIST research consortium.

Dr. Heinrich and Dr. Corless accepting the generous gift from Norman Scherzer of the Life Raft Group.
May 2008
The Gist Cancer Research Fund presented a generous donation in the amount of $150,000 to the Heinrich-Corless Research Lab on May 15th at the GCRF Grant Presentation Breakfast at OHSU. This support is greatly appreciated because, without these gifts, we would not be able to continue to help find a cure for this terrible disease.

Dr. Heinrich and Dr. Corless accepting the generous gift from The GIST Cancer Research Fund.