2017

  • Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033.  PMID: 28196207
  • PDGFRA Antibody for Soft Tissue Sarcoma.  Download PDF  PMID: 28187274


2016

  • ​​FGFR1 and NTRK3 actionable alterations in "Wild-Type" gastrointestinal stromal tumors.  Download PDF  PMID: 27974047
  • Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib.  PMID: 27167336
  • ​Dose-escalation study of a second-generation non-ansamycin HSP90 inhibitor, onalespib (AT13387), in combination with imatinib in patients with metastatic gastrointestinal stromal tumour.   Download PDF​  PMID: 27156227
  • Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial.  Download PDF   PMID: 26772734


2015

  • S0502: A SWOG Phase III Randomized Study of Imatinib, With or Without Bevacizumab, in Patients With Untreated Metastatic or Unresectable Gastrointestinal Stromal Tumors.  Download PDF   PMID: 26576593
  • Utility of BRAF V600E mutation-specific immunohistochemistry in detecting BRAF V600E-mutated gastrointestinal stromal tumors.  Download PDF  PMID: 26486743
  • SDHC methylation in gastrointestinal stromal tumors (GIST): a case report.  Download PDF  PMID: 26415883
  • Genotyping and immunohistochemistry of gastrointestinal stromal tumors: An update.  PMID: 25766843 
  • Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors.  Download PDF PMID: 25729899
  • Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition.  Download PDF  PMID: 25695690  
  • Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance.  Download PDF  PMID: 25432174  
  • Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways.  Download PDF  PMID: 25165019  


2014

  • Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).           Download PDF  PMID: 25239601
  • Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.  Download PDF  PMID: 25239608
  • Combination therapy for KIT-mutant mast cells: Targeting constitutive NFAT and KIT activity.  Download PDF            PMID: 25253785
  • Oncogenic mutations in melanomas and benign melanocytic nevi of the female genital tract.  Download PDF            PMID: 24842760
  • Regorafenib for treatment of advanced gastrointestinal stromal tumors. Download PDF  PMID: 24405315
  • KRAS and KIT Gatekeeper Mutations Confer Polyclonal Primary Imatinib Resistance in GI Stromal Tumors: Relevance of Concomitant Phosphatidylinositol 3-Kinase/AKT Dysregulation. PMID: 24687822
  • Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.  PMID: 24638003
  • Novel Mutations in Neuroendocrine Carcinoma of the Breast: Possible Therapeutic Targets.  Download PDF           PMID: 24569783
  • Gastrointestinal stromal tumors: what do we know now?  Download PDF  PMID: 24384849

 

2013

  • Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin. Download PDF  PMID: 23775962
  • Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia. Download PDF  PMID: 23705826
  • Gastrointestinal stromal tumour.Download PDF  PMID: 23623056
  • Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms. Download PDF  PMID: 23497317
  • Combining Highly Multiplexed PCR with Semiconductor-Based Sequencing for Rapid Cancer Genotyping.     PMID: 23274167
  • BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance. Download PDF  
  • Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.Download PDF  PMID: 23313954


2012

  • Multiplex mutation screening by mass spectrometry in gastrointestinal stromal tumours.  PMID: 22777070
  • Regorafenib Induces Rapid and Reversible Changes in Plasma Nitric Oxide and Endothelin-1.  Download PDF  PMID: 22785409
  • Crenolanib Inhibits the Drug-Resistant PDGFRA D842V Mutation Associated with Imatinib-resistant Gastrointestinal Stromal Tumors.  Download PDF  PMID: 22745105
  • Mucinous breast carcinomas lack PIK3CA and AKT1 mutations.   Download PDF  PMID: 22705004
  • Sorafenib Inhibits Many Kinase Mutations Associated with Drug-Resistant Gastrointestinal Stromal Tumors.  Download PDF  PMID: 22665524
  • Multiplex high-throughput gene mutation analysis in acute myeloid leukemia.  Download PDF  PMID: 22658276
  • Efficacy and Safety of Regorafenib in Patients With Metastatic and/or Unresectable GI Stromal Tumor After Failure of Imatinib and Sunitinib: A Multicenter Phase II Trial.  Download PDF  PMID: 22614970
  • Phase II trial of neoadjuvant/adjuvant imatinib mesylate for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumors: long-term follow-up results of Radiation Therapy Oncology Group 0132.  Download PDF  PMID: 22203182   Erratum to "Phase II..."  
  • Loss of succinate dehydrogenase subunit B (SDHB) expression is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours: a comprehensive genotype-phenotype correlation study.  Download PDF  PMID: 22804613


2011

  • Differential expression of neural markers in KIT and PDGFRA wild-type gastrointestinal stromal tumors.  Download PDF  PMID: 22175887
  • Gastrointestinal stromal tumours: origin and molecular oncology.   Download PDF  PMID: 22089421
  • A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients.  Download PDF  PMID: 21994214
  • Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective population-based study differ from those of advanced GISTs. Download PDF  PMID: 21953054
  • Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry. Download PDF  PMID: 21726664
  • ​"Pediatric-type" Gastrointestinal Stromal Tumors in Adults: Distinctive Histology Predicts Genotype and Clinical Behavior.  Download PDF  PMID: 21358303