Diana Griffith has been a proteomics Senior Research Assistant in Dr. Heinrich's lab since 1999. After mutations in C-KIT, PDGFRa, or K-RAS are found, Diana's responsibility is to express these mutant kinases in eukaryotic systems and use experimental kinase inhibitor drugs to see if kinase activity can be lessened in a dose that is therapeutically achievable. She also performs proliferation assays using the same group of inhibitor compounds on cells in culture that have naturally occurring tyrosine kinase mutations. Furthermore, she lyses and processes human tumor in order to visualize through Immunoprecipitation and Western Blot analysis the presence of constitutively active tyrosine kinases. Diana is from Southern California and has a BS in Cell and Developmental Biology from UC Santa Barbara.
Ashley Young is Dr. Heinrich's Admin Assistant and also gives general support to the Heinrich Lab. She received a BS in Human Development and Family Science with an option in Human Service from Oregon State University in 2005. When Ashley is not at work, she enjoys spending time with her family.
Arin McKinley is a Senior Research Assistant in Dr. Heinrich's laboratory and has been with the lab since May 2002. She earned her B.A. in Biology from the University of Iowa. Arin does cell culture, transfections, and protein expression experiments for the Heinirich Lab. Arin enjoys running, quilting, and exploring the Pacific Northwest with her family.
Tracy Walker has been an oncology research nurse for over 10 years, with a focus on GIST and renal cancer clinical trials. She graduated from Willamette University in Biology and the University of San Francisco in nursing. In her free time, she likes to run, bike and swim and spend time with her twins.
Ajia Town is a Senior Research Assistant in Dr. Heinrich's laboratory and has been with the lab since August 2001. She received a BS in Genetic Engineering with a minor in Chemistry from Southern Illinois University at Edwardsville in 1999. Ajia is responsible for sequencing, tissue culture, site-directed mutagenesis, DNA cloning, protein expression studies testing drug sensitivity, and maintaining the lab's website. She enjoys spending time in the outdoors with her daughter.
Lilli Klug is a post-doc with a PhD in Cancer Biology from OHSU and has been a part if the Heinrich lab since spring of 2012. She graduated with a B.S in Biology at Colorado State University in 2008. Lilli is investigating novel KIT regulatory proteins in GIST using human cell lines that model KIT-mutant tumors seen in patients.
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